请问如果用pass软件还原以下样本量计算过程,谢谢。The studies we
请问如果用pass软件还原以下样本量计算过程,谢谢。The studies were powered to detect a standardized effect size (treatment difference/standard deviation [SD]) of 0.42 for Study 1 and 0.33 for Study 2, with 90% power and a 0.05 significance level, under an assumed SD. This relates to a difference of 2.5 and 2 points in change from baseline in ADAS-Cog for Study 1 and 2, respectively (under an assumed SD of 6), and a difference of 0.47for CIBIC1 (under an assumed SD of 1.12) for Study 1 and a difference in change from baseline in CDR-SB of 0.6 for Study 2 (under an assumed SD of 1.8). This required 122 and 190 subjects per treatment group for Study 1 and 2, respectively.