请问这篇文章的方法有谁能解答下吗？ We created a summary index for each category of biomarkers to indicate the overall level of representative biomarkers in that category. We created a percentile variable for each of the biomarkers based on their original data and summarized the percentiles weighted by the number of biomarkers in a given category [e.g., the weights were 1/3 for biomarkers within the systemic inflammation category (n=3) and 1/ 5 for biomarkers within the coagulation category (n=5)]. In view that tPA is a protein involved in the breakdown of blood clots (Orth et al., 1992), we multiply the percentiles of tPA by “−1 (minus one)” before summarizing the weighted percentiles for coagulatory biomarkers. Therefore, a higher summary percentile of the index for coagulation indicates a higher coagulatory state. Fibrinogen is an acute-phase protein and may be elevated in any form of inflammation, and also helps in the formation of blood clots (Davalos and Akassoglou, 2012). Therefore, we included fibrinogen in the indices for systemic inflammation and coagulation simultaneously